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Clinical trials
23 February 2026
Type
Written Ministerial Statement
Department
Department of Health and Social Care
At a Glance
Issue Summary
Wes Streeting updates Parliament on the pause of preliminary work for the PATHWAYS clinical trial regarding puberty suppressants for gender incongruence.
Action Requested
The MHRA has raised concerns about the trial, and discussions to address these issues will begin this week. The trial will not proceed until safety and clinical evidence support its continuation.
Key Facts
- The preliminary work for the PATHWAYS clinical trial has been paused.
- The MHRA wrote a letter to King’s College London raising concerns about the trial.
- Discussions between the MHRA and King’s College London will address these new concerns this week.
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