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Modification of the NHS Fetal Anomaly Screening Programme to include screening for Edwards’ syndrome on the antenatal quadruple test
17 December 2025
Type
Written Ministerial Statement
Department
Department of Health and Social Care
At a Glance
Issue Summary
The minister is announcing a modification to the NHS Fetal Anomaly Screening Programme to include Edwards’ syndrome in the antenatal quadruple test.
Action Requested
The Department of Health and Social Care has accepted the UK National Screening Committee’s recommendation to add Edwards’ syndrome screening through the quadruple test for women who have not completed the first trimester combined test. This addition supports informed choice for pregnant women facing an increased chance of Edwards’ syndrome.
Key Facts
- Edwards’ syndrome, or Trisomy 18, affects 1 in 1500 pregnancies.
- The quadruple test is already used to screen for Down’s syndrome in the second trimester.
- Pregnant women who have not completed the first trimester combined test can now be offered the quadruple test for Edwards’ syndrome screening.
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