Today marks 12 weeks since Margaret Keenan became the first person in the world to receive a clinically approved vaccine for covid-19. Since then, over 20 million other citizens have been vaccinated in the biggest and fastest vaccination effort ever seen. This programme is a national success story, allowing protection from science to replace restrictions on freedoms. Data shows that hospital admissions are falling faster than new cases, with falls more pronounced among those first vaccinated. The halving time for hospital admissions is now 18 days, down to 15 days in over-85s recently. Deaths fell by over a quarter in mid-February according to the ONS, and daily deaths are halving every 12 days overall but faster in over-80s at 10 days. This indicates that vaccines are saving lives and protecting the NHS. Two new pieces of research show rising antibody levels up to 11 February (one in four people have antibodies) and a single dose reducing hospitalisations by more than 80% among over-70s. The minister thanked colleagues for promoting vaccine uptake, which has led to high enthusiasm globally. Over-60s are now being invited to be vaccinated. Despite lumpy supply figures, they expect bumper weeks ahead, and plan to offer vaccines to all priority groups by April 15th and all adults by July end. Investments in genomic sequencing helped detect variants early. Six cases of the P.1 variant from Brazil were identified; five quarantined at home legally, one case did not complete contact details successfully. The batch of test kits was narrowed down to 379 households in south-east England for further contact. They are working on understanding its impact and developing an updated vaccine if needed. Caution is advised as the virus can mutate quickly.